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Cofactor Genomics is so much more than a resource for sequencing. We provide real solutions that generate results to make a real difference in your research.
About Cofactor
What makes Cofactor tick is the people behind the service. We offer the perfect solution for your sequencing needs so you get the most out of your experiments.
Team Profiles
Cofactor Genomics offers the absolute best value in genomic sequencing today. That's because of our unique ability to deliver more than just sequencing.
Projects & Pricing
At Cofactor, we make it as easy as possible to submit your samples. It is our goal to streamline your experiment in the most efficient manner possible.
Sample Submission
Learn about Cofactor's web-based analysis and visualization software.
ActiveSite
Get started with your project by providing us with information about your goals.
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RNA-Seq
Each application takes biological samples through experimental design, sample preparation, sequencing, and application specific analysis, allowing us to engineer processes and deliverables that provide unparalleled insight into researchers' data.
RNA-Seq
Cofactor Genomics's robust RNA-seq pipeline provides researchers with the ability to evaluate differential gene expression in their chosen organism. ActiveSite, our intuitive web-based user-interface, enables researchers to examine, sort, and discover patterns in their data that may not be visible when working with text files or in classical expression applications. Our Project Scientists ensure that experiments survey transcriptomes at the appropriate depth. Whether a wide-overview or a deep interrogation, researchers will have confidence in the results we provide.
Deliverables
- FASTQ formatted Sequence Reads
- Annotations defining clusters of transcription
- Normalized expression values across all samples for each locus
Log2 Expression Ratios
Cofactor compares every sample against every other sample in a pair-wise fashion. This approach helps delineate and tier data outputs based on comparisons between replicate samples.
FASTA of the aligned regions
Cofactor delivers the FASTA sequence of every cluster of read alignments. This deliverable will closely represent the transcriptome assembly for the given sample.
Saturation Curves
Cofactor's saturation analysis offers the ability to determine, during the experimental design, the appropriate number of reads to generate for each sample. Using a proprietary saturation pipeline, Cofactor can graph the interaction of reads totals and unique transcript counts. When a transcriptome pool is sequenced to saturation, the resulting saturation curve will be asymptotic. This unique analysis allows us to determine the point where the most data is generated per dollar spent.
Assembly of non-mapping reads
Reads that do not align to the reference assembly may be important or interesting in the context of an RNA-seq experiment. We are able to assemble just the unaligned reads which may provide further clues to the etiology of a condition or contamination in a sample.
Access to data in Cofactor's ActiveSite Expression Viewer
Cofactor's ActiveSite Viewer is a web portal that hosts all of the information associated with a project. ActiveSite enables clients to examine, sort, and discover patterns in their data that may not be visible when working with just text files or in classical expression applications. Using the viewer, clients are also able to download the background files used to build their analysis.
Videos
RNA-seq Webinar
Video of our RNA-seq webinar, including a demo of our RNA-seq ActiveSite
Click here to play
Further Information
For more information, please contact our Sales Group:
1.888.8.COFACTOR | 314.531.4647
