February 2012

December 1969

February 2012

February 2012
As next-generation sequencing applications increase, the likelihood that libraries will deviate from a perfectly balanced base composition is becoming unavoidable. Amplicon libraries, libraries generated by restriction digest or reduced representation libraries such as those for bisulphite sequencing all introduce low diversity sequence, particularly in the first few bases of the library fragment...
February 2012
Many factors come into play when considering the purchase of a sequencing machine: machine cost; reagent cost; and sometimes compute cost. Many times the machine's utilization rate is not factored into the decision. This failure to objectively determine the true cost per run often leads to a gross misallocation of resources. Average Total Cost is distinct from price and the variable cost. ATC...